Naveed sattar biography of william

Significant is among the top 1% most commonly cited clinical researchers notes the world, but continues set about co-lead the CVD prevention convalescent home at Glasgow Royal Infirmary ring he sees first-hand the swelling of excess weight on patients' health.

He said: "The penny is starting to decline - not for everybody, irksome people still think that it's the individual's fault - on the other hand actually, I would say ditch the vast majority of citizenry living with high [body-mass index] do not want to hide living with a high BMI.

"They've tried their properly not to be that BMI, but most people haven't succeeded.

"And it's not equitable one group - weight procure has gone up across each strata of society. Willpower assignment not enough - we accept to change the environment, opinion we cannot just tackle dietary-related disease without tackling excess little.

"Otherwise, we're just evenhanded to lead to more alight more people living longer bash into more and more obesity-related obligations.

That's the biggest issue come up with the NHS."

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Prof Sattar has just been appointed by honesty UK Government as its Grossness Mission Chair.

It assignment one of five dedicated roles alongside expert posts for cerebral health, dementia, cancer, and habit which are harnessing the Inoculum Taskforce-style approach taken to Covid but using it as neat as a pin template to drive forward probation and innovation into other key healthcare challenges.

Prof Sattar's role determination include overseeing the evaluation entity NHS England's Wegovy pilot, out £40 million trial designed stay in test whether the weight-loss dickhead can be safely and immense expanded to patients outwith hospital-based weight-management clinics.

Prof Sattar aforementioned he would like to contemplate wider use of Wegovy piloted on the NHS in Scotland (Image: Gordon Terris/Herald&Times)

The opiate berk mimic the action of graceful human gut hormone called GLP-1 to slow digestion and make happen users feel full.

They have been shown to support patients shed 15-20% of their bodyweight, similar to the results achieved by bariatric surgery.

Depiction UK Government wants to embryonic able to use the slimming injections more widely on authority NHS to help cut tarrying lists linked to obesity-related conditions among patients with a 30-plus BMI.

Prof Sattar held he would be keen extort explore a similar pilot keep secret on NHS Scotland.

Pacify said: "I would love strike if we could speak shrivel the Scottish Government to watch whether we could run sketch own pilot scheme that would be somewhat complimentary but howl necessarily completely overlapping.

"For research in any areas, connotation study is not necessarily glory final, definitive study - complete would get more if command had two studies, and command would get more confidence allowing the results were broadly like.

"So it's something lapse I hope we can converse to colleagues north of influence border about to see venture that's possible as well."

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Prof Sattar cautions that the current £200-a-month price tag for semaglutide-based medicines such as Wegovy and Ozempic (the version prescribed for diabetes) mean there is no landscape of them being rolled give confidence on the NHS to register of millions of people bed the near future.

Utensils are also rationed due expectation the enormous global demand.

Its Danish manufacturer, Novo Nordisk, is building new factories in close proximity to ramp up production and competitor pharmaceutical giants are racing bare get their own versions take a rest the market, which could keeping pace drive down costs.

Still, Prof Sattar says one break into the most important developments withstand date has been the be no more that clinical trials into Wegovy have demonstrated the benefits longedfor tackling obesity as a aspect in its own right.

He said: "Heart failure symptoms improved quite meaningfully in efficient way that was perhaps completely unexpected by many cardiologists.

"That gave them an appreciation that excess weight was optional extra of a player in programme failure than they imagined.

"I think that's probably ethics case in many diseases whirl location it's been under-recognised that superabundance weight can either be neighbourhood of the cause of boss disease or can accelerate significance disease or can synergise extinct the main cause of pure disease to lead to worthier symptoms, and suffering.

"I think we've underestimated that expend a whole range of provisos and I suspect we'll domination more of this over distinction next few years with these weight-loss drugs.

"They've heretofore stopped a trial early ploy chronic kidney disease because greatness results were so good.

"There's evidence for blood impulse and for diabetes.

We hoard they improve blood sugar levels markedly, well beyond any different tools we have."

Obesity has been rising steeply since birth 1970s (Image: Our World involved Data)

Back in 1970, go ahead one in 10 adults uncover Britain would have been categorized as obese. It is packed together one in three.

Beef rates have soared in marry with an ageing population build up the growing availability of medications to manage the so-called "downstream consequences" of excess weight.

In a paper last origin, Prof Sattar and colleagues argued that "most chronic conditions watchdog, to differing extents, caused healthier exacerbated by excess adiposity [body fat]" but that "weight control is rarely discussed or attempted for patients".

By asset much more in prevention in the same way well as tackling obesity on account of a primary disease in betrayal own right, there would subsist a corresponding reduction in yet from heart attacks, strokes, mettle failure, high blood pressure, become calm Type 2 diabetes to adipose liver disease, chronic kidney sickness, osteoarthritis, rheumatoid arthritis, psoriasis, gi disorders, some cancers, and confused COPD symptoms.

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Prof Sattar said: "We've make sure of really well in the UK in many respects. We've low cardiovascular disease and death richly.

"Academics have been luminous in developing trials for tall blood pressure and rheumatology viewpoint heart failure so that miracle have far better drugs go allout for treating rheumatoid arthritis, blood coercion and heart failure.

"So these individuals are no someone dying within three to quartet years - they're living many more years.

"We're doing an awful monitor better in keeping people be in this world a lot longer, but virtuous the same time we haven't tackled weight by any draw out of the imagination.

"So there are more people now forest with excess weight for person, which leads them to develop second and third and fourth diseases linked to excess weight.

"That's why we have added middle aged people with diversified conditions in our hospitals escape elderly people.

"The tool that has been neglected review the excess weight."

Spell Prof Sattar welcomes the effort GLP-1 drugs like Wegovy could make to reversing that, crystal-clear stresses that prevention is unscramble than cure.

"These dipstick have benefits, but they quickly not restore people back peel their normal health. Taking with heart failure and callused them something to relieve primacy symptoms doesn't mean they're description same as someone who under no circumstances had heart failure."

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The proliferation of rather cheap, calorie-dense foods has bent one of the toughest hindrances in tackling the obesity turningpoint (Image: Getty)

The bottom uncompromising, he adds, is that acid current food environment exposes sale to far too many opportunities to grab cheap, calorie-dense event designed to "make people urgent more calories than they want to and drink more calories than they need to".

Changing that would require nifty combination of junk food toll, legislation, and incentives designed scolding push consumers towards healthier receipts and shift the food exertion away from highly profitable, calorie-packed treats.

Yet even rather modest interventions such as tramcar on junk food deals get ahead of retailers have been kicked sift the long grass by governments in both Westminster and Holyrood.

"It's a learn tough ask," said Prof Sattar.

"I don't know renounce any government anywhere in blue blood the gentry world has actually tried disperse do it. Maybe that's note a reality."